The California-based company is also planning to hire 130 professionals in India in areas like product engineering.
A company spokesperson, however, declined to comment.
Sources said the recent announcement of Yahoo!'s global layoff, will impact less than 4 per cent of Yahoo! India R&D's workforce, which at present is 1,500.
A significant number of the employees are being laid off on performance grounds, and some of them on account of reorganisation, leading to their becoming functionless. This move would allow the company to focus on strategic priorities and provide flexibility for targeted hiring in key business areas, they said.
Yahoo! would continue to hire in business-critical areas, in India. The company currently has over 130 openings, sources added.
This is the second lay-off Yahoo! India will be undertaking following global announcements. In December 2008, the company had served notices to three per cent of its India workforce due to the ongoing slowdown.